Many patients with chronic illness have acquired ‘obstacles to cure’. One of the most important of these in western society arises due to the derangement of bowel micro-ecology. So-called Dysbiosis can render patients chronically sick with features of toxicity, fatigue, impaired resistance, IBS and systemic disturbance. In this seminar, Dr Malcolm will revise the biology of the GI tract and explore the historical basis for the development of the Bowel Nosodes, he will then describe the materia medica of the nosodes and illustrate their effectiveness with case studies. Additionally, the mind pictures and remedy relationships will be explored and a specialized repertory for these materials will be introduced.